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Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas
The gene encoding the E3 ubiquitin ligase Ligand of Numb protein-X (Lnx)2a is expressed in the ventral-anterior pancreatic bud of zebrafish embryos in addition to its expression in the brain. Knockdown of Lnx2a by using an exon 2/intron 2 splice morpholino resulted in specific inhibition of the diff...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603503/ https://ncbi.nlm.nih.gov/pubmed/26392552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517033112 |
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