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Functionalization of a Rigid Divalent Ligand for LecA, a Bacterial Adhesion Lectin**

The bacterial adhesion lectin LecA is an attractive target for interference with the infectivity of its producer P. aeruginosa. Divalent ligands with two terminal galactoside moieties connected by an alternating glucose-triazole spacer were previously shown to be very potent inhibitors. In this stud...

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Bibliografiske detaljer
Udgivet i:ChemistryOpen
Main Authors: Fu, Ou, Pukin, Aliaksei V, Quarles van Ufford, H C, Kemmink, Johan, de Mol, Nico J, Pieters, Roland J
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603407/
https://ncbi.nlm.nih.gov/pubmed/26478841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402171
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