Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson's Disease

Pentoxifylline (PTX) is a phosphodiesterase inhibitor with anti-TNF-alpha activity, associated with its anti-inflammatory action. Considering Parkinson's disease (PD) as a neuroinflammatory disorder, the objectives were to evaluate PTX neuroprotective properties, in a model of PD. Male Wistar r...

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Detalhes bibliográficos
Publicado no:Parkinsons Dis
Main Authors: Neves, Kelly Rose Tavares, Nobre, Hélio Vitoriano, Leal, Luzia Kalyne A. M., de Andrade, Geanne Matos, Brito, Gerly Anne de Castro, Viana, Glauce Socorro de Barros
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603313/
https://ncbi.nlm.nih.gov/pubmed/26491600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/108179
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