Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas

Pentoxifylline (PTX), a methyl xanthine derivative, is a phosphodiesterase inhibitor with anti-inflammatory and renoprotective effects in diabetic patients, among other properties. We studied PTX actions and mechanisms in reducing blood biochemical parameters, in diabetic rats. For diabetes inductio...

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Detalhes bibliográficos
Main Authors: Garcia, Francisca Adilfa O, Pinto, Sofia F, Cavalcante, Andrezza F, Lucetti, Lívia T, Menezes, Silvana MS, Felipe, Cícero Francisco B, Alves, Ana Paula NN, Brito, Gerly Anne C, Cerqueira, Gilberto S, Viana, Glauce SB
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070224/
https://ncbi.nlm.nih.gov/pubmed/24991532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-283
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