Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase

Studies suggest that inflammation is a key factor in the pathogenesis of diabetes mellitus. Pro-inflammatory cytokines, such as IL-6 and TNF-alpha, are produced by adipose tissue in large quantities, in obese and especially in diabetic individuals. Pentoxifylline (PTX) is a non-selective phosphodies...

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Detalhes bibliográficos
Publicado no:J Inflamm (Lond)
Main Authors: Garcia, Francisca Adilfa de Oliveira, Rebouças, Jéssica Farias, Balbino, Teresa Queiroz, da Silva, Teresinha Gonçalves, de Carvalho-Júnior, Carlson Hélder Reis, Cerqueira, Gilberto Santos, Brito, Gerly Anne de Castro, Viana, Glauce Socorro de Barros
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4411660/
https://ncbi.nlm.nih.gov/pubmed/25922592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-015-0080-5
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