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Non-germline genetically engineered mouse models for translational cancer research
Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...
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Опубликовано в: : | Nat Rev Cancer |
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Главные авторы: | , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2010
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/ https://ncbi.nlm.nih.gov/pubmed/20574449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877 |
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