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Non-germline genetically engineered mouse models for translational cancer research

Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...

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Опубликовано в: :Nat Rev Cancer
Главные авторы: Heyer, Joerg, Kwong, Lawrence N., Lowe, Scott W., Chin, Lynda
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/
https://ncbi.nlm.nih.gov/pubmed/20574449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877
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