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Non-germline genetically engineered mouse models for translational cancer research

Genetically engineered mouse models (GEMMs) of cancer have affected virtually all areas of cancer research. However, the accelerated discovery of new cancer genes emerging from large-scale cancer genomics and new chemical entities pouring from the drug discovery pipeline have strained the capacity o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Cancer
Hauptverfasser: Heyer, Joerg, Kwong, Lawrence N., Lowe, Scott W., Chin, Lynda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602412/
https://ncbi.nlm.nih.gov/pubmed/20574449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2877
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