Nitrosative modifications of the Ca(2+) release complex and actin underlie arthritis-induced muscle weakness

OBJECTIVE: Skeletal muscle weakness is a prominent clinical feature in patients with rheumatoid arthritis (RA), but the underlying mechanism(s) is unknown. Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on int...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Yamada, Takashi, Fedotovskaya, Olga, Cheng, Arthur J, Cornachione, Anabelle S, Minozzo, Fabio C, Aulin, Cecilia, Fridén, Cecilia, Turesson, Carl, Andersson, Daniel C, Glenmark, Birgitta, Lundberg, Ingrid E, Rassier, Dilson E, Westerblad, Håkan, Lanner, Johanna T
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602262/
https://ncbi.nlm.nih.gov/pubmed/24854355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-205007
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