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The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation
Folate metabolism is central to cell proliferation and a target of commonly used cancer chemotherapeutics. In particular, the mitochondrial folate-coupled metabolism is thought to be important for proliferating cancer cells. The enzyme MTHFD2 in this pathway is highly expressed in human tumors and b...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602236/ https://ncbi.nlm.nih.gov/pubmed/26461067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15029 |
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