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Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3

Cartilage defect is an intractable clinical problem. Therapeutic strategies for cartilage repair are far from optimal due to poor proliferation capacity of chondrocytes. Autologous chondrocyte implantation is a cell based therapy that uses in vitro amplified healthy chondrocytes from the patient. Ho...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tian, Kang, Zhong, Weiliang, Zheng, Xifu, Zhang, Jinrui, Liu, Pixu, Zhang, Weiguo, Liu, Han
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602231/
https://ncbi.nlm.nih.gov/pubmed/26459914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15101
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