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Dissecting Alzheimer disease in Down syndrome using mouse models

Down syndrome (DS) is a common genetic condition caused by the presence of three copies of chromosome 21 (trisomy 21). This greatly increases the risk of Alzheimer disease (AD), but although virtually all people with DS have AD neuropathology by 40 years of age, not all develop dementia. To dissect...

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Detalhes bibliográficos
Publicado no:Front Behav Neurosci
Main Authors: Choong, Xun Yu, Tosh, Justin L., Pulford, Laura J., Fisher, Elizabeth M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602094/
https://ncbi.nlm.nih.gov/pubmed/26528151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2015.00268
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