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Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease

Down's syndrome (DS) in humans is caused by trisomy of chromosome 21 (HSA 21). DS patients have a variety of pathologies, including mental retardation and an unusually high incidence of leukemia or lymphoma such as megakaryocytic leukemia. Individuals with DS develop the characteristic neuropat...

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Detalhes bibliográficos
Main Authors: Levine, Seymour, Saltzman, Arthur, Levy, Efrat, Ginsberg, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659493/
https://ncbi.nlm.nih.gov/pubmed/19041304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2008.10.006
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