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Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway

The contribution of deficient telomerase activity to age-related decline in osteoblast functions and bone formation is poorly studied. We have previously demonstrated that telomerase over-expression led to enhanced osteoblast differentiation of human bone marrow skeletal (stromal) stem cells (hMSC)...

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Dades bibliogràfiques
Publicat a:Biogerontology
Autors principals: Saeed, Hamid, Qiu, Weimin, Li, Chen, Flyvbjerg, Allan, Abdallah, Basem M., Kassem, Moustapha
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602053/
https://ncbi.nlm.nih.gov/pubmed/26260615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-015-9596-6
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