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Polarity establishment requires localized activation of Cdc42

Establishment of cell polarity in animal and fungal cells involves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region destined to become the “front” of the cell. The high local concentration of active Cdc42 promotes cytoskeletal polarization through vari...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Woods, Benjamin, Kuo, Chun-Chen, Wu, Chi-Fang, Zyla, Trevin R., Lew, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602047/
https://ncbi.nlm.nih.gov/pubmed/26459595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506108
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