Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction

Progressive fibrosis is characterized by excessive deposition of extracellular matrix (ECM), resulting in gross alterations in tissue mechanics. Changes in tissue mechanics can further augment scar deposition through fibroblast mechanotransduction. In idiopathic pulmonary fibrosis, a fatal form of p...

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Publicat a:J Cell Biol
Autors principals: Fiore, Vincent F., Strane, Patrick W., Bryksin, Anton V., White, Eric S., Hagood, James S., Barker, Thomas H.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602038/
https://ncbi.nlm.nih.gov/pubmed/26459603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201505007
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