Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction

Progressive fibrosis is characterized by excessive deposition of extracellular matrix (ECM), resulting in gross alterations in tissue mechanics. Changes in tissue mechanics can further augment scar deposition through fibroblast mechanotransduction. In idiopathic pulmonary fibrosis, a fatal form of p...

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Pubblicato in:J Cell Biol
Autori principali: Fiore, Vincent F., Strane, Patrick W., Bryksin, Anton V., White, Eric S., Hagood, James S., Barker, Thomas H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602038/
https://ncbi.nlm.nih.gov/pubmed/26459603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201505007
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