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A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter
Mammalian with-no-lysine [K] (WNK) kinases are a family of four serine-threonine protein kinases, WNK1-4. Mutations of WNK1 and WNK4 in humans cause pseudohypoaldosteronism type II (PHA2), an autosomal-dominant disease characterized by hypertension and hyperkalemia. Increased Na(+) reabsorption thro...
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| Publié dans: | Pflugers Arch |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601926/ https://ncbi.nlm.nih.gov/pubmed/25904388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-015-1708-2 |
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