Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways

Background. Staphylococcus epidermidis causes late-onset sepsis in preterm infants. Staphylococcus epidermidis activates host responses in part via Toll-like receptor 2 (TLR2). Epidemiologic studies link bacteremia and neonatal brain injury, but direct evidence is lacking. Methods. Wild-type and TLR...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Bi, Dan, Qiao, Lili, Bergelson, Ilana, Ek, C. Joakim, Duan, Luqi, Zhang, Xiaoli, Albertsson, Anna-Maj, Pettengill, Matthew, Kronforst, Kenny, Ninkovic, Jana, Goldmann, Donald, Janzon, Anders, Hagberg, Henrik, Wang, Xiaoyang, Mallard, Carina, Levy, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601917/
https://ncbi.nlm.nih.gov/pubmed/25883383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv231
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