A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses.

Staphylococcus epidermidis (SE) causes late onset sepsis and significant morbidity in catheterized preterm newborns. Animal models of SE infection are useful in characterizing disease mechanisms and are an important approach to developing improved diagnostics and therapeutics. Current murine models...

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Main Authors: Kenny D Kronforst, Christy J Mancuso, Matthew Pettengill, Jana Ninkovic, Melanie R Power Coombs, Chad Stevens, Michael Otto, Carina Mallard, Xiaoyang Wang, Donald Goldmann, Ofer Levy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3435332?pdf=render
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