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Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis)

PURPOSE: To test the hypothesis that the accumulation of oxidized phospholipids (OxPL) in the macula is toxic to the retina unless neutralized by a variety of mechanisms, including binding by lipoprotein(a) [Lp(a)], which is composed of apolipoprotein(a) [apo(a)] and apolipoprotein B-100 (apoB). MET...

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Detalhes bibliográficos
Publicado no:Trans Am Ophthalmol Soc
Main Authors: Handa, James T., Tagami, Mizuki, Ebrahimi, Katayoon, Leibundgut, Gregor, Janiak, Anna, Witztum, Joseph L., Tsimikas, Sotirios
Formato: Artigo
Idioma:Inglês
Publicado em: The American Ophthalmological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601905/
https://ncbi.nlm.nih.gov/pubmed/26538774
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