A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

The objective of this study was to determine whether a grape seed procyanidin extract (GSPE) exerts a triglyceride-lowering effect in a hyperlipidemic state using the fructose-fed rat model and to elucidate the underlying molecular mechanisms. Rats were fed either a starch control diet or a diet con...

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Veröffentlicht in:PLoS One
Hauptverfasser: Downing, Laura E., Heidker, Rebecca M., Caiozzi, Gianella C., Wong, Brian S., Rodriguez, Kelvin, Del Rey, Fernando, Ricketts, Marie-Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601771/
https://ncbi.nlm.nih.gov/pubmed/26458107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140267
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