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A grape seed procyanidin extract inhibits HDAC activity leading to increased Pparα phosphorylation and target gene expression
SCOPE: Histone deacetylases (HDACs) have emerged as epigenetic regulators of risk factors associated with the metabolic syndrome (MetS), and certain botanical extracts have proven to be potent HDAC inhibitors. Understanding the role of dietary procyanidins in HDAC inhibition is important in explorin...
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Publicado no: | Mol Nutr Food Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292052/ https://ncbi.nlm.nih.gov/pubmed/27624175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201600347 |
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