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KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation

Phagocytosis of apoptotic cells by both professional and semi-professional phagocytes is required for resolution of organ damage and maintenance of immune tolerance. KIM-1/TIM-1 is a phosphatidylserine receptor that is expressed on epithelial cells and can transform the cells into phagocytes. Here,...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Brooks, Craig R, Yeung, Melissa Y, Brooks, Yang S, Chen, Hui, Ichimura, Takaharu, Henderson, Joel M, Bonventre, Joseph V
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601664/
https://ncbi.nlm.nih.gov/pubmed/26282792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489838
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