KIM-1–mediated phagocytosis reduces acute injury to the kidney

Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. Here, we determined that early in the injury process, however, KIM-1 expression is antiinflammatory due to its mediation of phagocytic proc...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Yang, Li, Brooks, Craig R., Xiao, Sheng, Sabbisetti, Venkata, Yeung, Melissa Y., Hsiao, Li-Li, Ichimura, Takaharu, Kuchroo, Vijay, Bonventre, Joseph V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396492/
https://ncbi.nlm.nih.gov/pubmed/25751064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75417
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