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Combining Active Immunization with Monoclonal Antibody Therapy to Facilitate Early Initiation of a Long-acting Anti-methamphetamine Antibody Response

We hypothesized that an anti-METH mAb could be used in combination with a METH-conjugate vaccine (MCV) to safely improve the overall quality and magnitude of the anti-METH immune response. The benefits would include immediate onset of action (from the mAb), timely increases in the immune responses (...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Hambuchen, Michael D., Carroll, F. Ivy, Rüedi-Bettschen, Daniela, Hendrickson, Howard P., Hennings, Leah J., Blough, Bruce E., Brieaddy, Lawrence E., Pidaparthi, Ramakrishna R., Owens, S. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601636/
https://ncbi.nlm.nih.gov/pubmed/25973614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00220
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