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Treatment of rats with an anti-(+)-methamphetamine monoclonal antibody shortens the duration of action of repeated (+)-methamphetamine challenges over a one month period
This study assessed clinical scenarios of continuing monoclonal antibody (mAb) treatment for (+)-methamphetamine (METH) addiction, and the implications of missing or discontinuing this therapy. We hypothesized that chronic anti-METH mAb7F9 (METH K(D) = 9 nM) treatment of rats could significantly dec...
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| Udgivet i: | Vaccine |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250301/ https://ncbi.nlm.nih.gov/pubmed/25252196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.09.025 |
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