Treatment of rats with an anti-(+)-methamphetamine monoclonal antibody shortens the duration of action of repeated (+)-methamphetamine challenges over a one month period

This study assessed clinical scenarios of continuing monoclonal antibody (mAb) treatment for (+)-methamphetamine (METH) addiction, and the implications of missing or discontinuing this therapy. We hypothesized that chronic anti-METH mAb7F9 (METH K(D) = 9 nM) treatment of rats could significantly dec...

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Vydáno v:Vaccine
Hlavní autoři: Hambuchen, Michael D., Rüedi-Bettschen, Daniela, Williams, D. Keith, Hendrickson, Howard, Owens, S. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250301/
https://ncbi.nlm.nih.gov/pubmed/25252196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.09.025
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