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Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking

Elastase is a serine protease from the chymotrypsin family of enzymes with the ability to degrade elastin, an important component of connective tissues. Excessive elastin proteolysis leads to a number of pathological diseases. Porcine pancreatic elastase (PPE) is often used for drug development as a...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Hofbauer, Stefan, Brito, José A., Mulchande, Jalmira, Nogly, Przemyslaw, Pessanha, Miguel, Moreira, Rui, Archer, Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601602/
https://ncbi.nlm.nih.gov/pubmed/26457529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15017045
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