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Purification, crystallization and X-ray crystallographic analysis of human RAB11(S20V), a constitutively active GTP-binding form

RAB11, a member of the Ras superfamily of small G proteins, is involved in the regulation of vesicle trafficking during endosome recycling. Substitution of Ser20 by Val20 in Rab11 [RAB11(S20V)] inhibits its GTP hydrolysis activity and produces a constitutively active GTP-binding form. In this study,...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Kim, Chang Min, Choi, Jae Young, Yoon, Jong Hwan, Park, Hyun Ho
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601587/
https://ncbi.nlm.nih.gov/pubmed/26457514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15015447
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