Synthetic Scrapie Infectivity: Interaction between Recombinant PrP and Scrapie Brain-Derived RNA

The key molecular event in human cerebral proteinopathies, which include Alzheimer's, Parkinson's and Huntington's diseases, is the structural conversion of a specific host protein into a β-sheet-rich conformer. With regards to this common mechanism, it appears difficult to explain th...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Simoneau, Steve, Thomzig, Achim, Ruchoux, Marie-Madeleine, Vignier, Nicolas, Daus, Martin L, Poleggi, Anna, Lebon, Pierre, Freire, Sophie, Durand, Valerie, Graziano, Silvia, Galeno, Roberta, Cardone, Franco, Comoy, Emmanuel, Pocchiari, Maurizio, Beekes, Michael, Deslys, Jean-Philippe, Fournier, Jean-Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601501/
https://ncbi.nlm.nih.gov/pubmed/25585171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.989795
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