Sensitive detection of aggregated prion protein via proximity ligation

The DNA assisted solid-phase proximity ligation assay (SP-PLA) provides a unique opportunity to specifically detect prion protein (PrP) aggregates by investigating the collocation of 3 or more copies of the specific protein. We have developed an SP-PLA that can detect PrP aggregates in brain homogen...

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Detalles Bibliográficos
Publicado en:Prion
Autores principales: Hammond, Maria, Wik, Lotta, Deslys, Jean-Philippe, Comoy, Emmanuel, Linné, Tommy, Landegren, Ulf, Kamali-Moghaddam, Masood
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601298/
https://ncbi.nlm.nih.gov/pubmed/25482604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.32231
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