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Sensitive detection of aggregated prion protein via proximity ligation
The DNA assisted solid-phase proximity ligation assay (SP-PLA) provides a unique opportunity to specifically detect prion protein (PrP) aggregates by investigating the collocation of 3 or more copies of the specific protein. We have developed an SP-PLA that can detect PrP aggregates in brain homogen...
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| Publicado en: | Prion |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601298/ https://ncbi.nlm.nih.gov/pubmed/25482604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.32231 |
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