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Directed evolution combined with synthetic biology strategies expedite semi-rational engineering of genes and genomes

Owing to our limited understanding of the relationship between sequence and function and the interaction between intracellular pathways and regulatory systems, the rational design of enzyme-coding genes and de novo assembly of a brand-new artificial genome for a desired functionality or phenotype ar...

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Bibliografski detalji
Izdano u:Bioengineered
Glavni autori: Kang, Zhen, Zhang, Junli, Jin, Peng, Yang, Sen
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601291/
https://ncbi.nlm.nih.gov/pubmed/25621864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2015.1011029
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