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Directed evolution combined with synthetic biology strategies expedite semi-rational engineering of genes and genomes

Owing to our limited understanding of the relationship between sequence and function and the interaction between intracellular pathways and regulatory systems, the rational design of enzyme-coding genes and de novo assembly of a brand-new artificial genome for a desired functionality or phenotype ar...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Kang, Zhen, Zhang, Junli, Jin, Peng, Yang, Sen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601291/
https://ncbi.nlm.nih.gov/pubmed/25621864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2015.1011029
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