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Pretreatment of chemically-synthesized Aβ(42) affects its biological activity in yeast

The tendency of amyloid β (Aβ(42)) peptide to misfold and aggregate into insoluble amyloid fibrils in Alzheimer's disease (AD) has been well documented. Accumulation of Aβ(42) fibrils has been correlated with abnormal apoptosis and unscheduled cell division which can also trigger the death of n...

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Bibliografische gegevens
Gepubliceerd in:Prion
Hoofdauteurs: Porzoor, Afsaneh, Caine, Joanne M, Macreadie, Ian G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601261/
https://ncbi.nlm.nih.gov/pubmed/25495906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336896.2014.992275
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