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Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation
[Image: see text] Combination with redox modulators can potentiate the anticancer activity and maximize the selectivity of organometallic complexes with redox-based mechanisms of action. We show that nontoxic doses of l-buthionine sulfoximine increase the selectivity of organo-Os complex FY26 for hu...
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| Veröffentlicht in: | J Med Chem |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2015
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601049/ https://ncbi.nlm.nih.gov/pubmed/26397305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00655 |
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