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A Mechanistic Collective Cell Model for Epithelial Colony Growth and Contact Inhibition

We present a mechanistic hybrid continuum-discrete model to simulate the dynamics of epithelial cell colonies. Collective cell dynamics are modeled using continuum equations that capture plastic, viscoelastic, and elastic deformations in the clusters while providing single-cell resolution. The conti...

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Detaylı Bibliyografya
Yayımlandı:Biophys J
Asıl Yazarlar: Aland, Sebastian, Hatzikirou, Haralambos, Lowengrub, John, Voigt, Axel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601048/
https://ncbi.nlm.nih.gov/pubmed/26445436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.003
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