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A Mechanistic Collective Cell Model for Epithelial Colony Growth and Contact Inhibition
We present a mechanistic hybrid continuum-discrete model to simulate the dynamics of epithelial cell colonies. Collective cell dynamics are modeled using continuum equations that capture plastic, viscoelastic, and elastic deformations in the clusters while providing single-cell resolution. The conti...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601048/ https://ncbi.nlm.nih.gov/pubmed/26445436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.003 |
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