Postmitotic Expression of SOD1(G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation

To determine the role of mutant SOD1 gene (SOD1(G93A)) on muscle cell differentiation, we derived C2C12 muscle cell lines carrying a stably transfected SOD1(G93A) gene under the control of a myosin light chain (MLC) promoter-enhancer cassette. Expression of MLC/SOD1(G93A) in C2C12 cells resulted in...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Martini, Martina, Dobrowolny, Gabriella, Aucello, Michela, Musarò, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600922/
https://ncbi.nlm.nih.gov/pubmed/26491230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/537853
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