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Two-photon fluorescence lifetime imaging of primed SNARE complexes in presynaptic terminals and β cells

It remains unclear how readiness for Ca(2+)-dependent exocytosis depends on varying degrees of SNARE complex assembly. Here we directly investigate the SNARE assembly using two-photon fluorescence lifetime imaging (FLIM) of Förster resonance energy transfer (FRET) between three pairs of neuronal SNA...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Takahashi, Noriko, Sawada, Wakako, Noguchi, Jun, Watanabe, Satoshi, Ucar, Hasan, Hayashi-Takagi, Akiko, Yagishita, Sho, Ohno, Mitsuyo, Tokumaru, Hiroshi, Kasai, Haruo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600761/
https://ncbi.nlm.nih.gov/pubmed/26439845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9531
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