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State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines

Dendritic spines are the postsynaptic sites of most excitatory synapses in the brain, and spine enlargement and shrinkage give rise to long-term potentiation and depression of synapses, respectively. Because spine structural plasticity is accompanied by remodeling of actin scaffolds, we hypothesized...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Noguchi, Jun, Hayama, Tatsuya, Watanabe, Satoshi, Ucar, Hasan, Yagishita, Sho, Takahashi, Noriko, Kasai, Haruo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011767/
https://ncbi.nlm.nih.gov/pubmed/27595610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32897
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