Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors

Myelin regeneration can occur spontaneously in demyelinating diseases such as multiple sclerosis (MS). However, the underlying mechanisms and causes of its frequent failure remain incompletely understood. Here we show, using an in-vivo remyelination model, that demyelinated axons are electrically ac...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Gautier, Hélène O. B., Evans, Kimberley A., Volbracht, Katrin, James, Rachel, Sitnikov, Sergey, Lundgaard, Iben, James, Fiona, Lao-Peregrin, Cristina, Reynolds, Richard, Franklin, Robin J. M., Káradóttir, Ragnhildur T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600759/
https://ncbi.nlm.nih.gov/pubmed/26439639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9518
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