Neuregulin and BDNF Induce a Switch to NMDA Receptor-Dependent Myelination by Oligodendrocytes

Myelination is essential for rapid impulse conduction in the CNS, but what determines whether an individual axon becomes myelinated remains unknown. Here we show, using a myelinating coculture system, that there are two distinct modes of myelination, one that is independent of neuronal activity and...

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Detalhes bibliográficos
Main Authors: Lundgaard, Iben, Luzhynskaya, Aryna, Stockley, John H., Wang, Zhen, Evans, Kimberley A., Swire, Matthew, Volbracht, Katrin, Gautier, Hélène O. B., Franklin, Robin J. M., ffrench-Constant, Charles, Attwell, David, Káradóttir, Ragnhildur T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876980/
https://ncbi.nlm.nih.gov/pubmed/24391468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001743
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