miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program

Macrophages play a pivotal role in tissue fibrogenesis, which underlies the pathogenesis of many end-stage chronic inflammatory diseases. MicroRNAs are key regulators of immune cell functions, but their roles in macrophage's fibrogenesis have not been characterized. Here we show that IL-4 and I...

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Vydáno v:Nat Commun
Hlavní autoři: Su, Shicheng, Zhao, Qiyi, He, Chonghua, Huang, Di, Liu, Jiang, Chen, Fei, Chen, Jianing, Liao, Jian-You, Cui, Xiuying, Zeng, Yunjie, Yao, Herui, Su, Fengxi, Liu, Qiang, Jiang, Shanping, Song, Erwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600756/
https://ncbi.nlm.nih.gov/pubmed/26436920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9523
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