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Up-regulation of miR-21 Mediates Resistance to Trastuzumab Therapy for Breast Cancer
Trastuzumab resistance emerges to be a major issue in anti-human epidermal growth factor receptor 2 (HER2) therapy for breast cancers. Here, we demonstrated that miR-21 expression was up-regulated and its function was elevated in HER2(+) BT474, SKBR3, and MDA-MB-453 breast cancer cells that are indu...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099726/ https://ncbi.nlm.nih.gov/pubmed/21471222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216887 |
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