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Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation
Development of acute experimental autoimmune encephalomyelitis (EAE) depends on Th17 cells expressing the nuclear factor NR4A2. However, in mice lacking NR4A2 in T cells, a late-onset disease is still inducible, despite a great reduction in acute inflammation. We here reveal that development of this...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600741/ https://ncbi.nlm.nih.gov/pubmed/26436530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9437 |
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