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Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions

Human β-defensin 3 (HBD3) is a prominent host defense peptide. In our recent work, we observed that HBD3 modulates pro-inflammatory agonist-induced chemokine and cytokine responses in human myeloid dendritic cells (DCs), often at 20.0 μM concentrations. Since HBD3 can be cytotoxic in some circumstan...

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Detalhes bibliográficos
Publicado no:Toxicol Lett
Main Authors: Leelakanok, Nattawut, Fischer, Carol L., Bates, Amber M., Guthmiller, Janet M., Johnson, Georgia K., Salem, Aliasger K., Brogden, Kim A., Brogden, Nicole K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600674/
https://ncbi.nlm.nih.gov/pubmed/26367466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2015.09.006
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