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Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification

RATIONALE: Endothelial cells have the ability to undergo endothelial-mesenchymal transitions (EndMTs), by which they acquire a mesenchymal phenotype and stem-cell like characteristics. We previously found that EndMTs ocurred in the endothelium deficient in matrix Gla protein (MGP) enabling endotheli...

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Bibliographic Details
Published in:Circ Res
Main Authors: Yao, Jiayi, Guihard, Pierre J., Blazquez-Medela, Ana M., Guo, Yina, Moon, Jeremiah H., Jumabay, Medet, Boström, Kristina I., Yao, Yucheng
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600461/
https://ncbi.nlm.nih.gov/pubmed/26265629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306751
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