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Hyper-osmolarity and calcium chelation: Effects on cystic fibrosis mucus

A non-functional Cystic Fibrosis Transmembrane conductance Regulator (CFTR) leads to the disease cystic fibrosis (CF). Although the CFTR is expressed in multiple organs, pulmonary disease is the major cause of illness and death in patients with CF. Stagnant mucus, causing airway obstruction, bacteri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Pharmacol
Hauptverfasser: Ermund, Anna, Meiss, Lauren N., Gustafsson, Jenny K., Hansson, Gunnar C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600443/
https://ncbi.nlm.nih.gov/pubmed/26134505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2015.06.051
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