TLR4 mutant mice are protected from renal fibrosis and chronic kidney disease progression

Chronic kidney disease (CKD) is associated with persistent low-grade inflammation and immunosuppression. In this study we tested the role of Toll-like receptor 4, the main receptor for endotoxin (LPS), in a mouse model of renal fibrosis and in a model of progressive CKD that better resembles the hum...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Souza, Ana C P, Tsuji, Takayuki, Baranova, Irina N, Bocharov, Alexander V, Wilkins, Kenneth J, Street, Jonathan M, Alvarez-Prats, Alejandro, Hu, Xuzhen, Eggerman, Thomas, Yuen, Peter S T, Star, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600397/
https://ncbi.nlm.nih.gov/pubmed/26416975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12558
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