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Chronic kidney disease-induced HMGB1 elevation worsens sepsis and sepsis-induced acute kidney injury
We previously showed that kidney dysfunction/interstitial fibrosis by folate predisposes mice to sepsis mortality (normal/sepsis: 15%; folate/sepsis: 90%); agents that increased survival in normal septic mice were ineffective in the two-stage model. We used a recently characterized 5/6 nephrectomy (...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491658/ https://ncbi.nlm.nih.gov/pubmed/21832986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.261 |
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