Pre-existing Renal Disease Promotes Sepsis-induced Acute Kidney Injury and Worsens Sepsis Outcome via Multiple Pathways

Patients with chronic kidney disease (CKD) are at significantly higher risk of death from sepsis, although the mechanism by which CKD increases mortality has not been investigated. We established a mouse two-stage model of pre-existing renal disease with subsequent sepsis by combining folic acid (FA...

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Detalhes bibliográficos
Main Authors: Doi, Kent, Leelahavanichkul, Asada, Hu, Xuzhen, Sidransky, Karen L., Qin, Yan, Eisner, Christoph, Schnermann, Jurgen, Yuen, Peter S. T., Star, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614371/
https://ncbi.nlm.nih.gov/pubmed/18633340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.346
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