Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis

BACKGROUND: Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim of the study was to describethe genome wide DNA methylation changes in hip and knee OA and identify novel genes and pathwaysinvolved in OA by comparing the DNA methylome of the hip and knee osteoarthritic cart...

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Publicado en:BMC Musculoskelet Disord
Autores principales: Aref-Eshghi, Erfan, Zhang, Yuhua, Liu, Ming, Harper, Patricia E., Martin, Glynn, Furey, Andrew, Green, Roger, Sun, Guang, Rahman, Proton, Zhai, Guangju
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600269/
https://ncbi.nlm.nih.gov/pubmed/26453558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-015-0745-5
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